Mus musculus Gene: Car7
Summary
InnateDB Gene IDBG-185712.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Car7
Gene Name carbonic anhydrase 7
Synonyms AV343731; Ca7
Species Mus musculus
Ensembl Gene ENSMUSG00000031883
Encoded Proteins
carbonic anhydrase 7
carbonic anhydrase 7
carbonic anhydrase 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168748:
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the salivary glands. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:104534700-104550343
Strand Forward strand
Band D3
Transcripts
ENSMUST00000056051 ENSMUSP00000052136
ENSMUST00000159416 ENSMUSP00000125112
ENSMUST00000162761 ENSMUSP00000125404
ENSMUST00000162399
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0032230 positive regulation of synaptic transmission, GABAergic
GO:0032849 positive regulation of cellular pH reduction
GO:2001225 regulation of chloride transport
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Metabolism pathway
Reversible hydration of carbon dioxide pathway
KEGG
Nitrogen metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Reversible hydration of carbon dioxide pathway
Metabolism pathway
KEGG
Nitrogen metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q9ERQ8
TrEMBL G3XA26
UniProt Splice Variant
Entrez Gene 12354
UniGene Mm.129265
RefSeq NM_053070 XM_006530613 XM_006530615 XM_006530614 XM_006530616 XM_006530617 XM_006530618
OMIM
CCDS CCDS22581
HPRD
IMGT
MGI ID MGI:103100
MGI Symbol Car7
EMBL AC130543 AF291660 AY075021 BC094913 CH466525
GenPept AAG16230 AAH94913 AAL78169 EDL11220
RNA Seq Atlas 12354