Homo sapiens Gene: CHST9
Summary
InnateDB Gene IDBG-1858.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHST9
Gene Name carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154080
Encoded Proteins
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:26906481-27185317
Strand Reverse strand
Band q11.2
Transcripts
ENST00000284224 ENSP00000284224
ENST00000580774 ENSP00000464655
ENST00000581714 ENSP00000462852
ENST00000618847 ENSP00000480991
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity
GO:0008146 sulfotransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006790 sulfur compound metabolic process
GO:0016051 carbohydrate biosynthetic process
GO:0030166 proteoglycan biosynthetic process
GO:0030203 glycosaminoglycan metabolic process
GO:0030204 chondroitin sulfate metabolic process
GO:0030206 chondroitin sulfate biosynthetic process
GO:0042446 hormone biosynthetic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005576 extracellular region
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001256316 NM_031422 XM_005258362
HUGO
OMIM
CCDS CCDS42422 CCDS58618
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas