Mus musculus Gene: C3ar1
Summary
InnateDB Gene IDBG-185906.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C3ar1
Gene Name complement component 3a receptor 1
Synonyms AZ3B; C3AR; HNFAG09
Species Mus musculus
Ensembl Gene ENSMUSG00000040552
Encoded Proteins
complement component 3a receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
C3a and its receptor C3ar1 are critical for defense against C. psittaci in mouse lung infection.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171860:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:122847138-122856161
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000042081 ENSMUSP00000048092
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004943 C3a anaphylatoxin receptor activity
Biological Process
GO:0006935 chemotaxis
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0010575 positive regulation vascular endothelial growth factor production
GO:0010759 positive regulation of macrophage chemotaxis
GO:0045087 innate immune response (InnateDB)
GO:0045766 positive regulation of angiogenesis
GO:0090023 positive regulation of neutrophil chemotaxis
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Complement and coagulation cascades pathway
Staphylococcus aureus infection pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (i) signalling events pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Complement and coagulation cascades pathway
Staphylococcus aureus infection pathway
INOH
PID NCI
Cross-References
SwissProt O09047
TrEMBL Q3U4N3 Q5U7A4
UniProt Splice Variant
Entrez Gene 12267
UniGene Mm.2408
RefSeq NM_009779
OMIM
CCDS CCDS20504
HPRD
IMGT
MGI ID MGI:1097680
MGI Symbol C3ar1
EMBL AF053757 AK154134 AK154229 AK154609 AY786554 BC003728 CH466523 EU007909 U77460 U77461 U97537
GenPept AAB71814 AAC40193 AAC53203 AAC53204 AAH03728 AAV51803 ABV02577 BAE32398 BAE32449 BAE32711 EDK99698
RNA Seq Atlas 12267