Mus musculus Gene: Polr1c | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-186564.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Polr1c | ||||||||||||||||||||||
Gene Name | polymerase (RNA) I polypeptide C | ||||||||||||||||||||||
Synonyms | 40kDa; AA409007; AA959927; AL024089; Polr1e; RPA40; Rpo1-1 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000067148 | ||||||||||||||||||||||
Encoded Proteins |
polymerase (RNA) I polypeptide C
polymerase (RNA) I polypeptide C
polymerase (RNA) I polypeptide C
polymerase (RNA) I polypeptide C
polymerase (RNA) I polypeptide C
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171453:
The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome (TCS). [provided by RefSeq, Mar 2011] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 17:46243920-46248054 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | C | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Innate Immune System pathway
RNA Polymerase I Transcription pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Mus musculus biological processes pathway
NoRC negatively regulates rRNA expression pathway
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase I Transcription Termination pathway
NoRC negatively regulates rRNA expression pathway
Immune System pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
RNA Polymerase III Abortive And Retractive Initiation pathway
Epigenetic regulation of gene expression pathway
Cytosolic sensors of pathogen-associated DNA pathway
Gene Expression pathway
Negative epigenetic regulation of rRNA expression pathway
RNA Polymerase III Transcription Termination pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Promoter Clearance pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase III Transcription pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase I Transcription Initiation pathway
RNA Polymerase III Chain Elongation pathway
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KEGG |
Pyrimidine metabolism pathway
RNA polymerase pathway
Purine metabolism pathway
Cytosolic DNA-sensing pathway pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
TNFalpha pathway
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REACTOME |
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase III Transcription Termination pathway
RNA Polymerase III Chain Elongation pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase I Transcription Termination pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Transcription Initiation pathway
RNA Polymerase I Transcription pathway
RNA Polymerase III Transcription Initiation pathway
Innate Immune System pathway
Epigenetic regulation of gene expression pathway
RNA Polymerase I Promoter Clearance pathway
NoRC negatively regulates rRNA expression pathway
Immune System pathway
RNA Polymerase III Transcription pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Cytosolic sensors of pathogen-associated DNA pathway
Gene Expression pathway
Negative epigenetic regulation of rRNA expression pathway
RNA Polymerase III Transcription pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase I Transcription Termination pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
Cytosolic sensors of pathogen-associated DNA pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Transcription pathway
Gene Expression pathway
Immune System pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase I Transcription Initiation pathway
Innate Immune System pathway
RNA Polymerase I Promoter Clearance pathway
RNA Polymerase III Chain Elongation pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase III Transcription Termination pathway
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KEGG |
Pyrimidine metabolism pathway
Purine metabolism pathway
RNA polymerase pathway
Cytosolic DNA-sensing pathway pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | D3Z3D6 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 20016 | ||||||||||||||||||||||
UniGene | Mm.3458 | ||||||||||||||||||||||
RefSeq | NM_009085 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS37632 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:103288 | ||||||||||||||||||||||
MGI Symbol | Polr1c | ||||||||||||||||||||||
EMBL | AC116739 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 20016 | ||||||||||||||||||||||