Homo sapiens Gene: ANKFY1
Summary
InnateDB Gene IDBG-18666.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANKFY1
Gene Name ankyrin repeat and FYVE domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185722
Encoded Proteins
ankyrin repeat and FYVE domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a cytoplasmic protein that contains a coiled-coil structure and a BTB/POZ domain at its N-terminus, ankyrin repeats in the middle portion, and a FYVE-finger motif at its C-terminus. This protein belongs to a subgroup of double zinc finger proteins which may be involved in vesicle or protein transport. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:4163907-4263977
Strand Reverse strand
Band p13.2
Transcripts
ENST00000341657 ENSP00000343362
ENST00000574736 ENSP00000459247
ENST00000575509
ENST00000570934
ENST00000575298 ENSP00000467522
ENST00000575955
ENST00000572412 ENSP00000460619
ENST00000574367 ENSP00000459775
ENST00000573250
ENST00000571547
ENST00000572564
ENST00000570535 ENSP00000459943
ENST00000573722
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005765 lysosomal membrane
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9P2R3
TrEMBL I3L1Z9
UniProt Splice Variant
Entrez Gene 51479
UniGene Hs.513875 Hs.709943
RefSeq NM_016376 NM_001257999 XM_005256679
HUGO HGNC:20763
OMIM 607927
CCDS CCDS42236 CCDS58502
HPRD 09717
IMGT
EMBL AB033081 AB037360 AC087292 AC087742 AK292930 BC052308 CH471108
GenPept AAH52308 BAA86569 BAA90300 BAF85619 EAW90448
RNA Seq Atlas 51479