Version 5.4
Mus musculus Gene: Rap2a
Summary
InnateDB Gene IDBG-187472.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rap2a
Gene Name RAS related protein 2a
Synonyms 5830461H18Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000051615
Encoded Proteins
IDBP-187474
RAS related protein 2a
IDBP-536388
RAS related protein 2a
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125249:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:120478461-120507194
Strand Forward strand
Band E4
Transcripts
ENSMUST00000062117 ENSMUSP00000056433
ENSMUST00000156694 ENSMUSP00000118923
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0015093 ferrous iron transmembrane transporter activity
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0015684 ferrous iron transport
GO:0030336 negative regulation of cell migration
GO:0031532 actin cytoskeleton reorganization
GO:0031954 positive regulation of protein autophosphorylation
GO:0032486 Rap protein signal transduction
GO:0034613 cellular protein localization
GO:0045184 establishment of protein localization
GO:0046328 regulation of JNK cascade
GO:0048814 regulation of dendrite morphogenesis
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030496 midbody
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125249
View Gene Order
ENSBTAG00000020412
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_12
BCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q80ZJ1
TrEMBL
UniProt Splice Variant
Entrez Gene 76108
UniGene Mm.261448 Mm.409033
RefSeq NM_029519
OMIM
CCDS CCDS27341
HPRD
IMGT
MGI ID MGI:97855
MGI Symbol Rap2a
EMBL AK018024 AK140318 BC043066 BC049084 BC053003
GenPept AAH43066 AAH49084 AAH53003 BAB31042 BAE24330
RNA Seq Atlas 76108

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca