Mus musculus Gene: Gm10116
Summary
InnateDB Gene IDBG-187530.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gm10116
Gene Name predicted pseudogene 10116
Synonyms Ftl; Ftl-1; L-ferritin
Species Mus musculus
Ensembl Gene ENSMUSG00000062382
Encoded Proteins
predicted pseudogene 10116
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000087086:
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:74406396-74407317
Strand Forward strand
Band C1
Transcripts
ENSMUST00000090860 ENSMUSP00000088372
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008199 ferric iron binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 cellular iron ion homeostasis
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Iron uptake and transport pathway
Golgi Associated Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
Transmembrane transport of small molecules pathway
trans-Golgi Network Vesicle Budding pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
Scavenging by Class A Receptors pathway
Membrane Trafficking pathway
Iron uptake and transport pathway
Transmembrane transport of small molecules pathway
Scavenging by Class A Receptors pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q9CPX4 Q9CWA4 Q9CZE7
UniProt Splice Variant
Entrez Gene 434624
UniGene Mm.486189
RefSeq XM_003688879
OMIM
CCDS
HPRD
IMGT
MGI ID MGI:3779109
MGI Symbol Gm10116
EMBL AC151602 AK002242 AK002253 AK002547 AK011009 AK011029 AK011244 AK012690 AK088647 AK150480 AK151255 AK152030 AK152385 AK152393 AK152564 AK152612 AK159574 AK168735 AK168862 AK168866 AK169100 AK169159 BC081462 BC083350 BC085309 BC092259 BC106146 CH466563 CT009486
GenPept AAH81462 AAH83350 AAH85309 AAH92259 AAI06147 BAB21959 BAB21967 BAB22178 BAB27328 BAB27345 BAB27491 BAB28414 BAC40475 BAE29596 BAE30244 BAE30889 BAE31173 BAE31181 BAE31317 BAE31357 BAE35195 BAE40576 BAE40681 BAE40685 BAE40883 BAE40938 EDL37096 EDL37097
RNA Seq Atlas 100862446 14325 434624