Version 5.4
| Mus musculus Gene: Col8a2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-188398.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Col8a2 | ||||||||
| Gene Name | collagen, type VIII, alpha 2 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000056174 | ||||||||
| Encoded Proteins |
collagen, type VIII, alpha 2
collagen, type VIII, alpha 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171812:
This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. [provided by RefSeq, Dec 2009] This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 4:126286793-126314330 | ||||||||
| Strand | Forward strand | ||||||||
| Band | D2.2 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Collagen formation pathway
Assembly of collagen fibrils and other multimeric structures pathway
Collagen biosynthesis and modifying enzymes pathway
Extracellular matrix organization pathway
Integrin cell surface interactions pathway
Degradation of the extracellular matrix pathway
Collagen degradation pathway
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| KEGG | |||||||||
| INOH |
Integrin signaling pathway pathway
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| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Integrin cell surface interactions pathway
Assembly of collagen fibrils and other multimeric structures pathway
Collagen biosynthesis and modifying enzymes pathway
Collagen degradation pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
Collagen formation pathway
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| KEGG | |||||||||
| INOH |
Integrin signaling pathway pathway
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| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | A3KFY1 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 329941 | ||||||||
| UniGene | Mm.296327 Mm.395267 | ||||||||
| RefSeq | NM_199473 XM_006503187 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS18649 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:88464 | ||||||||
| MGI Symbol | Col8a2 | ||||||||
| EMBL | AL606976 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 329941 | ||||||||