Version 5.4
Mus musculus Gene: Stx8
Summary
InnateDB Gene IDBG-188576.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stx8
Gene Name syntaxin 8
Synonyms 0610007H08Rik; 1110002H11Rik; 4930571E13Rik; CARB
Species Mus musculus
Ensembl Gene ENSMUSG00000020903
Encoded Proteins
IDBP-188578
syntaxin 8
IDBP-188580
syntaxin 8
IDBP-264034
syntaxin 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170310:
The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:67966193-68207148
Strand Forward strand
Band B3
Transcripts
ENSMUST00000021286 ENSMUSP00000021286
ENSMUST00000021285 ENSMUSP00000021285
ENSMUST00000108675 ENSMUSP00000104315
ENSMUST00000129992
ENSMUST00000148642
ENSMUST00000142649
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000149 SNARE binding
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006906 vesicle fusion
GO:0008333 endosome to lysosome transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
GO:0031902 late endosome membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000170310
View Gene Order
ENSBTAG00000017815
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q9D0J1
UniProt Splice Variant
Entrez Gene 55943
UniGene Mm.3973
RefSeq XM_006533758 NM_018768 XM_006533757
OMIM
CCDS CCDS24863
HPRD
IMGT
MGI ID MGI:1890156
MGI Symbol Stx8
EMBL AK011376 AL663076 AL669842 BC061118 CH466601
GenPept AAH61118 BAB27578 EDL10443
RNA Seq Atlas 55943

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca