InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cenpt

Summary

InnateDB Gene

IDBG-188814.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cenpt

Gene Name

centromere protein T

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000036672

Encoded Proteins

IDBP-188816

centromere protein T

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102901:
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:105844678-105852008

Strand

Reverse strand

Band

Transcripts

ENSMUST00000040776

ENSMUSP00000038188

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0000278	mitotic cell cycle
GO:0007059	chromosome segregation
GO:0007067	mitotic nuclear division
GO:0051276	chromosome organization
GO:0051382	kinetochore assembly