Mus musculus Gene: Cenpt
Summary
InnateDB Gene IDBG-188814.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cenpt
Gene Name centromere protein T
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036672
Encoded Proteins
centromere protein T
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102901:
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:105844678-105852008
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000040776 ENSMUSP00000038188
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000278 mitotic cell cycle
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0051276 chromosome organization
GO:0051382 kinetochore assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Cell Cycle, Mitotic pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Cell Cycle pathway
M Phase pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Mitotic Anaphase pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Separation of Sister Chromatids pathway
Mitotic Prometaphase pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q3TJM4
TrEMBL
UniProt Splice Variant
Entrez Gene 320394
UniGene Mm.334775
RefSeq NM_177150
OMIM
CCDS CCDS22615
HPRD
IMGT
MGI ID MGI:2443939
MGI Symbol Cenpt
EMBL AK089172 AK090340 AK143613 AK164039 AK167376 BC022690 BC121824
GenPept AAH22690 AAI21825 BAC40776 BAC41176 BAE25464 BAE37599 BAE39471
RNA Seq Atlas 320394