InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Col11a1

Summary

InnateDB Gene

IDBG-189345.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col11a1

Gene Name

collagen, type XI, alpha 1

Synonyms

C530001D20Rik; cho

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027966

Encoded Proteins

IDBP-189349

collagen, type XI, alpha 1

IDBP-539304

collagen, type XI, alpha 1

IDBP-789297

collagen, type XI, alpha 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000060718:
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:114030540-114220718

Strand

Forward strand

Band

Transcripts

ENSMUST00000092155	ENSMUSP00000089793
ENSMUST00000123619	ENSMUSP00000121027
ENSMUST00000138680
ENSMUST00000184978	ENSMUSP00000138879

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005201	extracellular matrix structural constituent
GO:0046872	metal ion binding

Biological Process

GO:0001502	cartilage condensation
GO:0001503	ossification
GO:0002063	chondrocyte development
GO:0003007	heart morphogenesis
GO:0006029	proteoglycan metabolic process
GO:0007601	visual perception
GO:0007605	sensory perception of sound
GO:0030199	collagen fibril organization
GO:0035989	tendon development
GO:0042472	inner ear morphogenesis
GO:0048704	embryonic skeletal system morphogenesis
GO:0048705	skeletal system morphogenesis
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
GO:0051216	cartilage development
GO:0055010	ventricular cardiac muscle tissue morphogenesis