Version 5.4
Mus musculus Gene: Syncrip
Summary
InnateDB Gene IDBG-190151.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Syncrip
Gene Name synaptotagmin binding, cytoplasmic RNA interacting protein
Synonyms 2610109K23Rik; 4632417O19Rik; GRY-RBP; Nsap1; Nsap1l; pp68
Species Mus musculus
Ensembl Gene ENSMUSG00000032423
Encoded Proteins
IDBP-190153
synaptotagmin binding, cytoplasmic RNA interacting protein
IDBP-622291
synaptotagmin binding, cytoplasmic RNA interacting protein
IDBP-622301
synaptotagmin binding, cytoplasmic RNA interacting protein
IDBP-622303
synaptotagmin binding, cytoplasmic RNA interacting protein
IDBP-622305
synaptotagmin binding, cytoplasmic RNA interacting protein
IDBP-622307
synaptotagmin binding, cytoplasmic RNA interacting protein
IDBP-622309
synaptotagmin binding, cytoplasmic RNA interacting protein
IDBP-622310
synaptotagmin binding, cytoplasmic RNA interacting protein
IDBP-622312
synaptotagmin binding, cytoplasmic RNA interacting protein
IDBP-622315
synaptotagmin binding, cytoplasmic RNA interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135316:
This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:88449731-88482574
Strand Reverse strand
Band E3.1
Transcripts
ENSMUST00000069221 ENSMUSP00000063744
ENSMUST00000174391 ENSMUSP00000134342
ENSMUST00000174688 ENSMUSP00000133716
ENSMUST00000174269 ENSMUSP00000134506
ENSMUST00000174282 ENSMUSP00000134071
ENSMUST00000172828 ENSMUSP00000133829
ENSMUST00000173801 ENSMUSP00000133649
ENSMUST00000174361 ENSMUSP00000134722
ENSMUST00000174145
ENSMUST00000173405 ENSMUSP00000133343
ENSMUST00000172508 ENSMUSP00000133292
ENSMUST00000187770
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 109 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 109 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008143 poly(A) binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0017148 negative regulation of translation
GO:0070934 CRD-mediated mRNA stabilization
GO:0071346 cellular response to interferon-gamma
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0030529 ribonucleoprotein complex
GO:0070937 CRD-mediated mRNA stability complex
GO:0071013 catalytic step 2 spliceosome
GO:0071204 histone pre-mRNA 3'end processing complex
GO:0097452 GAIT complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135316
View Gene Order
ENSBTAG00000006672
Not yet available
Cross-References
SwissProt
TrEMBL G3UWM1 G3XA76
UniProt Splice Variant
Entrez Gene 56403
UniGene Mm.260545 Mm.375507 Mm.397281 Mm.406409 Mm.415780
RefSeq NM_001284328 NM_019666 NM_019796 XM_006511294 XM_006511295
OMIM
CCDS CCDS23388 CCDS57686 CCDS72292
HPRD
IMGT
MGI ID MGI:1891690
MGI Symbol Syncrip
EMBL CT025673
GenPept
RNA Seq Atlas 56403

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca