Version 5.4
Homo sapiens Gene: PELP1
Summary
InnateDB Gene IDBG-19211.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PELP1
Gene Name proline, glutamate and leucine rich protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141456
Encoded Proteins
IDBP-19213
Uncharacterized protein
IDBP-362569
Uncharacterized protein
IDBP-758560
IDBP-764539
IDBP-757673
IDBP-760664
IDBP-758696
IDBP-764519
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:4671385-4704337
Strand Reverse strand
Band p13.2
Transcripts
ENST00000301396 ENSP00000301396
ENST00000436683 ENSP00000416231
ENST00000573506
ENST00000570387 ENSP00000461419
ENST00000575534
ENST00000571347
ENST00000570571 ENSP00000460959
ENST00000571170
ENST00000575101 ENSP00000458985
ENST00000570823
ENST00000572293 ENSP00000460300
ENST00000574876 ENSP00000461625
ENST00000573523
ENST00000573242
ENST00000575329 ENSP00000461380
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 84 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 84 [view]
Protein-Protein 76 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0071339 MLL1 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000018921
View Gene Order
ENSBTAG00000018315
Not yet available
Pathways
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID NCI
ar_nongenomic_pathway
Nongenotropic Androgen signaling
ar_pathway
Coregulation of Androgen receptor activity
er_nongenomic_pathway
Plasma membrane estrogen receptor signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 27043
UniGene Hs.741234
RefSeq NM_001278241 NM_014389
HUGO HGNC:30134
OMIM 609455
CCDS CCDS58503 CCDS62038
HPRD 10144
IMGT
EMBL
GenPept
RNA Seq Atlas 27043

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca