Mus musculus Gene: Ldhd
Summary
InnateDB Gene IDBG-193454.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ldhd
Gene Name lactate dehydrogenase D
Synonyms 4733401P21Rik; D8Bwg1320e;
Species Mus musculus
Ensembl Gene ENSMUSG00000031958
Encoded Proteins
lactate dehydrogenase D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166816:
The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:111623785-111630374
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000070004 ENSMUSP00000068086
ENSMUST00000173909
ENSMUST00000173521
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004458 D-lactate dehydrogenase (cytochrome) activity
GO:0005515 protein binding
GO:0008720 D-lactate dehydrogenase activity
GO:0008762 UDP-N-acetylmuramate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006754 ATP biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Metabolism of proteins pathway
Mitochondrial protein import pathway
KEGG
Pyruvate metabolism pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of proteins pathway
Mitochondrial protein import pathway
KEGG
Pyruvate metabolism pathway
INOH
Glycolysis Gluconeogenesis pathway
Pyruvate metabolism pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q7TNG8
TrEMBL
UniProt Splice Variant
Entrez Gene 52815
UniGene Mm.27589
RefSeq NM_027570 XM_006531183
OMIM
CCDS CCDS22677
HPRD
IMGT
MGI ID MGI:106428
MGI Symbol Ldhd
EMBL AK037996 AY092768 BC039155 BC055443
GenPept AAH39155 AAH55443 AAM50323 BAC29917
RNA Seq Atlas 52815