Mus musculus Gene: Slc16a7
Summary
InnateDB Gene IDBG-193628.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc16a7
Gene Name solute carrier family 16 (monocarboxylic acid transporters), member 7
Synonyms 4921534N07Rik; Mct2
Species Mus musculus
Ensembl Gene ENSMUSG00000020102
Encoded Proteins
solute carrier family 16 (monocarboxylic acid transporters), member 7
solute carrier family 16 (monocarboxylic acid transporters), member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118596:
This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:125226464-125328963
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000063318 ENSMUSP00000065433
ENSMUST00000105257 ENSMUSP00000100892
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015129 lactate transmembrane transporter activity
GO:0015293 symporter activity
GO:0015355 secondary active monocarboxylate transmembrane transporter activity
GO:0050833 pyruvate transmembrane transporter activity
Biological Process
GO:0015711 organic anion transport
GO:0035873 lactate transmembrane transport
GO:0055085 transmembrane transport
GO:1901475 pyruvate transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
Proton-coupled monocarboxylate transport pathway
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Proton-coupled monocarboxylate transport pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.29161 Mm.394644
RefSeq NM_011391 XM_006513412
OMIM
CCDS CCDS24218
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas