Mus musculus Gene: Med11
Summary
InnateDB Gene IDBG-194345.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Med11
Gene Name mediator of RNA polymerase II transcription, subunit 11 homolog (S. cerevisiae)
Synonyms 1110030J09Rik; AI465144; AW545069;
Species Mus musculus
Ensembl Gene ENSMUSG00000018923
Encoded Proteins
mediator of RNA polymerase II transcription, subunit 11 homolog (S. cerevisiae)
mediator of RNA polymerase II transcription, subunit 11 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161920:
MED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:70451919-70453727
Strand Forward strand
Band B3
Transcripts
ENSMUST00000019067 ENSMUSP00000019067
ENSMUST00000151013 ENSMUSP00000134323
ENSMUST00000152348
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0008150 biological_process
Cellular Component
GO:0005654 nucleoplasm
GO:0016592 mediator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transcriptional regulation of white adipocyte differentiation pathway
Mus musculus biological processes pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
PPARA activates gene expression pathway
Developmental Biology pathway
Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
PPARA activates gene expression pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Transcriptional regulation of white adipocyte differentiation pathway
Metabolism pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9D8C6
TrEMBL G3UZ31
UniProt Splice Variant
Entrez Gene 66172
UniGene
RefSeq NM_025397
OMIM
CCDS CCDS24947
HPRD
IMGT
MGI ID MGI:1913422
MGI Symbol Med11
EMBL AK003984 AK008153 AL596096 BC025057 CR936841
GenPept AAH25057 BAB25497 BAE43156 CAI51988 CAM28187
RNA Seq Atlas 66172