Version 5.4
Mus musculus Gene: Hipk3
Summary
InnateDB Gene IDBG-194397.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hipk3
Gene Name homeodomain interacting protein kinase 3
Synonyms DYRK6; FIST3; PKY
Species Mus musculus
Ensembl Gene ENSMUSG00000027177
Encoded Proteins
IDBP-194399
homeodomain interacting protein kinase 3
IDBP-258788
homeodomain interacting protein kinase 3
IDBP-258790
homeodomain interacting protein kinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110422:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:104426481-104494446
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000028600 ENSMUSP00000028600
ENSMUST00000111125 ENSMUSP00000106754
ENSMUST00000111124 ENSMUSP00000106753
ENSMUST00000132622
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009299 mRNA transcription
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0043066 negative regulation of apoptotic process
GO:0043388 positive regulation of DNA binding
GO:0043508 negative regulation of JUN kinase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016605 PML body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110422
View Gene Order
ENSBTAG00000014884
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.257925 Mm.393464
RefSeq NM_001145824 NM_010434
OMIM
CCDS CCDS16489
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca