Version 5.4
Mus musculus Gene: Dnajc24
Summary
InnateDB Gene IDBG-195271.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnajc24
Gene Name DnaJ (Hsp40) homolog, subfamily C, member 24
Synonyms 1700030A21Rik; 2610027M02Rik; AV066965; AW240712; Dph4; MmDjC7; Zcsl3
Species Mus musculus
Ensembl Gene ENSMUSG00000027166
Encoded Proteins
IDBP-195273
DnaJ (Hsp40) homolog, subfamily C, member 24
IDBP-532730
DnaJ (Hsp40) homolog, subfamily C, member 24
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170946:
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:105966709-106003549
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000102555 ENSMUSP00000099615
ENSMUST00000155811 ENSMUSP00000122029
ENSMUST00000124163
ENSMUST00000151581
ENSMUST00000133569
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001671 ATPase activator activity
GO:0008198 ferrous iron binding
GO:0008270 zinc ion binding
Biological Process
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine
GO:0032781 positive regulation of ATPase activity
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000170946
View Gene Order
ENSBTAG00000032200
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 99349
UniGene Mm.25661
RefSeq NM_026992
OMIM
CCDS CCDS16501
HPRD
IMGT
MGI ID MGI:1919522
MGI Symbol Dnajc24
EMBL
GenPept
RNA Seq Atlas 99349

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca