InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Chrm5

Summary

InnateDB Gene

IDBG-196720.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Chrm5

Gene Name

cholinergic receptor, muscarinic 5

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000074939

Encoded Proteins

IDBP-196722

cholinergic receptor, muscarinic 5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184984:
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:112479171-112480769

Strand

Reverse strand

Band

Transcripts

ENSMUST00000099589

ENSMUSP00000097185

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0016907	G-protein coupled acetylcholine receptor activity
GO:0016934	extracellular-glycine-gated chloride channel activity

Biological Process

GO:0001696	gastric acid secretion
GO:0006821	chloride transport
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
GO:0015872	dopamine transport
GO:0019226	transmission of nerve impulse
GO:0060304	regulation of phosphatidylinositol dephosphorylation
GO:1902476	chloride transmembrane transport