InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: KAT6A

Summary

InnateDB Gene

IDBG-19708.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KAT6A

Gene Name

K(lysine) acetyltransferase 6A

Synonyms

MOZ; MYST3; RUNXBP2; ZC2HC6A; ZNF220

Species

Homo sapiens

Ensembl Gene

ENSG00000083168

Encoded Proteins

IDBP-19710

K(lysine) acetyltransferase 6A

IDBP-236460

K(lysine) acetyltransferase 6A

IDBP-294109

K(lysine) acetyltransferase 6A

IDBP-369116

K(lysine) acetyltransferase 6A

IDBP-369119

K(lysine) acetyltransferase 6A

IDBP-481846

K(lysine) acetyltransferase 6A

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:41929479-42051990

Strand

Reverse strand

Band

p11.21

Transcripts

ENST00000265713	ENSP00000265713
ENST00000396930	ENSP00000380136
ENST00000406337	ENSP00000385888
ENST00000418721	ENSP00000399638
ENST00000426524	ENSP00000396699
ENST00000485568	ENSP00000430606
ENST00000470574
ENST00000463961

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	37 [view]
Protein-Protein	31 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	6 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003713	transcription coactivator activity
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008270	zinc ion binding
GO:0016407	acetyltransferase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process

GO:0003007	heart morphogenesis
GO:0006323	DNA packaging
GO:0006325	chromatin organization
GO:0006334	nucleosome assembly
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006473	protein acetylation
GO:0008152	metabolic process
GO:0016573	histone acetylation
GO:0030099	myeloid cell differentiation
GO:0035019	somatic stem cell maintenance
GO:0035162	embryonic hemopoiesis
GO:0035909	aorta morphogenesis
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043966	histone H3 acetylation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0060325	face morphogenesis
GO:0090398	cellular senescence

Cellular Component

GO:0000786	nucleosome
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005794	Golgi apparatus
GO:0016605	PML body
GO:0070776	MOZ/MORF histone acetyltransferase complex

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000031540

View Gene Order

ENSBTAG00000004015

Not yet available

Pathways

NETPATH

REACTOME

REACT_172610

HATs acetylate histones pathway

REACT_172623

Chromatin organization pathway

REACT_172633

Chromatin modifying enzymes pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.491577 Hs.678582 Hs.682445 Hs.692861

RefSeq

NM_001099412 NM_001099413 NM_006766 XM_005273649

HUGO

OMIM

CCDS

CCDS6124

HPRD

03244

IMGT

EMBL

GenPept

RNA Seq Atlas