Mus musculus Gene: Sep15
Summary
InnateDB Gene IDBG-197615.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sep15
Gene Name selenoprotein
Synonyms 9430015P09Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000037072
Encoded Proteins
selenoprotein
selenoprotein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3\' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. The exact function of this protein is not known, however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this selenoprotein in the ER, where it may play a role in protein folding. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:144570304-144597680
Strand Forward strand
Band H2
Transcripts
ENSMUST00000082437 ENSMUSP00000046910
ENSMUST00000106211 ENSMUSP00000101817
ENSMUST00000144859
ENSMUST00000151086
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008430 selenium binding
Biological Process
GO:0051084 'de novo' posttranslational protein folding
Cellular Component
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_053102
OMIM
CCDS CCDS17884
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas