Version 5.4
Mus musculus Gene: Vps39
Summary
InnateDB Gene IDBG-200650.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vps39
Gene Name vacuolar protein sorting 39 (yeast)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000027291
Encoded Proteins
IDBP-200652
vacuolar protein sorting 39 (yeast)
IDBP-200654
vacuolar protein sorting 39 (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166887:
This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. [provided by RefSeq, Jul 2008]
This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:120316461-120353137
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000102501 ENSMUSP00000099559
ENSMUST00000028752 ENSMUSP00000028752
ENSMUST00000129857
ENSMUST00000133260
ENSMUST00000145193
ENSMUST00000147085
ENSMUST00000132476
ENSMUST00000138854
ENSMUST00000156296
ENSMUST00000126526
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005083 small GTPase regulator activity
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005765 lysosomal membrane
GO:0030897 HOPS complex
GO:0031902 late endosome membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166887
View Gene Order
ENSBTAG00000032055
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.246131
RefSeq NM_147153 NM_178851 XM_006499598 XM_006499599
OMIM
CCDS CCDS16619 CCDS38210
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca