Version 5.4
Mus musculus Gene: Mtap4
Summary
InnateDB Gene IDBG-201668.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtap4
Gene Name microtubule-associated protein 4
Synonyms AA407148; MAP-4; Mtap-4; Mtap4
Species Mus musculus
Ensembl Gene ENSMUSG00000032479
Encoded Proteins
IDBP-201670
microtubule-associated protein 4
IDBP-627049
microtubule-associated protein 4
IDBP-627051
microtubule-associated protein 4
IDBP-627052
microtubule-associated protein 4
IDBP-627053
microtubule-associated protein 4
IDBP-627055
microtubule-associated protein 4
IDBP-627056
microtubule-associated protein 4
IDBP-627058
microtubule-associated protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000047849:
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:109931460-110083947
Strand Forward strand
Band F2
Transcripts
ENSMUST00000035055 ENSMUSP00000035055
ENSMUST00000165876 ENSMUSP00000132662
ENSMUST00000163190 ENSMUSP00000130904
ENSMUST00000164930 ENSMUSP00000131285
ENSMUST00000163979 ENSMUSP00000129362
ENSMUST00000164234 ENSMUSP00000132460
ENSMUST00000167948 ENSMUSP00000132019
ENSMUST00000169851 ENSMUSP00000131660
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0015631 tubulin binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0007052 mitotic spindle organization
GO:0051012 microtubule sliding
GO:0051294 establishment of spindle orientation
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0015630 microtubule cytoskeleton
GO:0070062 extracellular vesicular exosome
GO:0072686 mitotic spindle
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000047849
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.217318 Mm.397306 Mm.408026 Mm.409650 Mm.416604 Mm.443428 Mm.472982 Mm.473470 Mm.484451
RefSeq NM_001205330 NM_001205331 NM_001205332 NM_008633 XM_006511952 XM_006511953 XM_006511954 XM_006511955 XM_006511956 XM_006511961 XM_006511963 XM_006511966 XM_006511967
OMIM
CCDS CCDS57703 CCDS57704
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca