InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Fshr

Summary

InnateDB Gene

IDBG-201758.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fshr

Gene Name

follicle stimulating hormone receptor

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000032937

Encoded Proteins

IDBP-201760

follicle stimulating hormone receptor

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170820:
The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:88985170-89200612

Strand

Reverse strand

Band

Transcripts

ENSMUST00000035701

ENSMUSP00000040477

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004963	follicle-stimulating hormone receptor activity
GO:0005515	protein binding
GO:0017046	peptide hormone binding

Biological Process

GO:0001541	ovarian follicle development
GO:0001545	primary ovarian follicle growth
GO:0001932	regulation of protein phosphorylation
GO:0003073	regulation of systemic arterial blood pressure
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007283	spermatogenesis
GO:0007286	spermatid development
GO:0007626	locomotory behavior
GO:0009992	cellular water homeostasis
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway
GO:0022602	ovulation cycle process
GO:0031175	neuron projection development
GO:0032350	regulation of hormone metabolic process
GO:0033044	regulation of chromosome organization
GO:0033146	regulation of intracellular estrogen receptor signaling pathway
GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
GO:0035092	sperm chromatin condensation
GO:0035093	spermatogenesis, exchange of chromosomal proteins
GO:0042699	follicle-stimulating hormone signaling pathway
GO:0043408	regulation of MAPK cascade
GO:0045056	transcytosis
GO:0045670	regulation of osteoclast differentiation
GO:0045779	negative regulation of bone resorption
GO:0060009	Sertoli cell development
GO:0060011	Sertoli cell proliferation
GO:0060065	uterus development
GO:0060408	regulation of acetylcholine metabolic process
GO:0071711	basement membrane organization