Version 5.4
Mus musculus Gene: Nek8
Summary
InnateDB Gene IDBG-202264.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nek8
Gene Name NIMA (never in mitosis gene a)-related expressed kinase 8
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000017405
Encoded Proteins
IDBP-202268
NIMA (never in mitosis gene a)-related expressed kinase 8
IDBP-623799
NIMA (never in mitosis gene a)-related expressed kinase 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a NIMA-related kinase. Members of this serine/threonine protein kinase family are structurally-related to NIMA (never in mitosis, gene A) which controls mitotic signaling in Aspergillus nidulans. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:78166106-78176675
Strand Reverse strand
Band B5
Transcripts
ENSMUST00000017549 ENSMUSP00000017549
ENSMUST00000152611
ENSMUST00000125528
ENSMUST00000131015
ENSMUST00000141444
ENSMUST00000147798
ENSMUST00000142812
ENSMUST00000148154 ENSMUSP00000127554
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0009887 organ morphogenesis
GO:0035330 regulation of hippo signaling
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0072372 primary cilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000160602
View Gene Order
ENSBTAG00000015535
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.23788 Mm.474794
RefSeq NM_080849 XM_006532184
OMIM
CCDS CCDS25091
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca