InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Fzd9

Summary

InnateDB Gene

IDBG-203698.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fzd9

Gene Name

frizzled homolog 9 (Drosophila)

Synonyms

mfz9

Species

Mus musculus

Ensembl Gene

ENSMUSG00000049551

Encoded Proteins

IDBP-203700

frizzled homolog 9 (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188763:
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]
Members of the \'frizzled\' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:135248938-135251230

Strand

Reverse strand

Band

Transcripts

ENSMUST00000062572

ENSMUSP00000053551

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0017147	Wnt-protein binding
GO:0030165	PDZ domain binding
GO:0042803	protein homodimerization activity
GO:0042813	Wnt-activated receptor activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001944	vasculature development
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007166	cell surface receptor signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007405	neuroblast proliferation
GO:0007420	brain development
GO:0007611	learning or memory
GO:0008406	gonad development
GO:0016055	Wnt signaling pathway
GO:0030183	B cell differentiation
GO:0060070	canonical Wnt signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031527	filopodium membrane
GO:0048471	perinuclear region of cytoplasm