Version 5.4
Mus musculus Gene: Exog
Summary
InnateDB Gene IDBG-204723.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Exog
Gene Name endo/exonuclease (5'-3'), endonuclease G-like
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000042787
Encoded Proteins
IDBP-204725
endo/exonuclease (5'-3'), endonuclease G-like
IDBP-627882
endo/exonuclease (5'-3'), endonuclease G-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157036:
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]
This gene encodes an endo/exonuclease with 5\'-3\' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5\' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:119444923-119465517
Strand Forward strand
Band F3
Transcripts
ENSMUST00000035094 ENSMUSP00000035094
ENSMUST00000164213 ENSMUSP00000129273
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000737 DNA catabolic process, endonucleolytic
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000157036
View Gene Order
ENSBTAG00000019305
Not yet available
Cross-References
SwissProt Q8C163
TrEMBL E9PZS5
UniProt Splice Variant
Entrez Gene 208194
UniGene
RefSeq NM_001172136 NM_172456
OMIM
CCDS CCDS23616 CCDS52964
HPRD
IMGT
MGI ID MGI:2143333
MGI Symbol Exog
EMBL AC121922 AC166052 AK028887 AK148426 AK162566 AK163555 BC119024
GenPept AAI19025 BAC26174 BAE28548 BAE36970 BAE37396
RNA Seq Atlas 208194

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca