InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Pgd

Summary

InnateDB Gene

IDBG-204947.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pgd

Gene Name

phosphogluconate dehydrogenase

Synonyms

0610042A05Rik; AU019875; C78335

Species

Mus musculus

Ensembl Gene

ENSMUSG00000028961

Encoded Proteins

IDBP-204949

phosphogluconate dehydrogenase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142657:
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:149149991-149166771

Strand

Reverse strand

Band

Transcripts

ENSMUST00000084124	ENSMUSP00000081141
ENSMUST00000124409
ENSMUST00000156120
ENSMUST00000137982
ENSMUST00000143944

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
GO:0050661	NADP binding

Biological Process

GO:0006098	pentose-phosphate shunt
GO:0009051	pentose-phosphate shunt, oxidative branch
GO:0019322	pentose biosynthetic process
GO:0019521	D-gluconate metabolic process
GO:0055114	oxidation-reduction process