Mus musculus Gene: Errfi1
Summary
InnateDB Gene IDBG-205853.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Errfi1
Gene Name ERBB receptor feedback inhibitor 1
Synonyms 1300002F13Rik; AI788755; Mig-6; Mig6; RALT;
Species Mus musculus
Ensembl Gene ENSMUSG00000028967
Encoded Proteins
ERBB receptor feedback inhibitor 1
ERBB receptor feedback inhibitor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116285:
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:150853919-150868892
Strand Forward strand
Band E2
Transcripts
ENSMUST00000073600 ENSMUSP00000073285
ENSMUST00000030811 ENSMUSP00000030811
ENSMUST00000128640
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
Biological Process
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity
GO:0031953 negative regulation of protein autophosphorylation
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0043589 skin morphogenesis
GO:0045616 regulation of keratinocyte differentiation
GO:0048286 lung alveolus development
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
GO:0060426 lung vasculature development
GO:0060428 lung epithelium development
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
EGFR1 pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q99JZ7
TrEMBL Q3TK48
UniProt Splice Variant
Entrez Gene 74155
UniGene Mm.318841 Mm.475529
RefSeq NM_133753 XM_006537088 XM_006539210
OMIM
CCDS CCDS18974
HPRD
IMGT
MGI ID MGI:1921405
MGI Symbol Errfi1
EMBL AK166791 AK167156 BC005546 BC057646 CH466594
GenPept AAH05546 AAH57646 BAE39021 BAE39297 EDL14895
RNA Seq Atlas 74155