Version 5.4
Mus musculus Gene: Gins1
Summary
InnateDB Gene IDBG-209422.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gins1
Gene Name GINS complex subunit 1 (Psf1 homolog)
Synonyms 2810418N01Rik; Gins4; mKIAA0186; PSF1
Species Mus musculus
Ensembl Gene ENSMUSG00000027454
Encoded Proteins
IDBP-209424
GINS complex subunit 1 (Psf1 homolog)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101003:
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:150905400-150931280
Strand Forward strand
Band G3
Transcripts
ENSMUST00000028948 ENSMUSP00000028948
ENSMUST00000152991
ENSMUST00000140950
ENSMUST00000123217
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001833 inner cell mass cell proliferation
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101003
View Gene Order
ENSBTAG00000019984
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_258062
Synthesis of DNA pathway
REACT_241296
DNA strand elongation pathway
REACT_232628
DNA Replication pathway
REACT_217374
Unwinding of DNA pathway
REACT_188804
Cell Cycle pathway
REACT_253623
S Phase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_6776
Unwinding of DNA pathway
REACT_383
DNA Replication pathway
REACT_2014
Synthesis of DNA pathway
REACT_899
S Phase pathway
REACT_115566
Cell Cycle pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_932
DNA strand elongation pathway
REACT_225014
S Phase pathway
REACT_213604
DNA Replication pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_224922
Synthesis of DNA pathway
REACT_214934
Cell Cycle pathway
REACT_219301
Unwinding of DNA pathway
REACT_203054
DNA strand elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9CZ15
TrEMBL
UniProt Splice Variant
Entrez Gene 69270
UniGene Mm.271603
RefSeq NM_027014
OMIM
CCDS CCDS50743
HPRD
IMGT
MGI ID MGI:1916520
MGI Symbol Gins1
EMBL AK013116
GenPept BAB28658
RNA Seq Atlas 69270

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca