Mus musculus Gene: Abi3
Summary
InnateDB Gene IDBG-209662.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abi3
Gene Name ABI gene family, member 3
Synonyms 2210414K06Rik; AI987680; NESH
Species Mus musculus
Ensembl Gene ENSMUSG00000018381
Encoded Proteins
ABI gene family, member 3
ABI gene family, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108798:
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates Rac-dependent actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:95830074-95842476
Strand Reverse strand
Band D
Transcripts
ENSMUST00000059026 ENSMUSP00000061893
ENSMUST00000131049
ENSMUST00000137645 ENSMUSP00000119990
ENSMUST00000143492
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0030334 regulation of cell migration
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0030027 lamellipodium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.485545
RefSeq NM_001163464 NM_025659 XM_006533954 XM_006533955 XM_006533957
OMIM
CCDS CCDS25283
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas