Version 5.4
Mus musculus Gene: Dusp15
Summary
InnateDB Gene IDBG-209929.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dusp15
Gene Name dual specificity phosphatase-like 15
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000042662
Encoded Proteins
IDBP-209933
dual specificity phosphatase-like 15
IDBP-261593
dual specificity phosphatase-like 15
IDBP-534745
dual specificity phosphatase-like 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149599:
The protein encoded by this gene belongs to the non-receptor class of the protein-tyrosine phosphatase family. The encoded protein has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:152940997-152951698
Strand Reverse strand
Band H1
Transcripts
ENSMUST00000037715 ENSMUSP00000045815
ENSMUST00000109811 ENSMUSP00000105436
ENSMUST00000123121 ENSMUSP00000123090
ENSMUST00000185197
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0042127 regulation of cell proliferation
GO:0046330 positive regulation of JNK cascade
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000149599
View Gene Order
ENSBTAG00000009005
Not yet available
Cross-References
SwissProt Q8R4V2
TrEMBL
UniProt Splice Variant
Entrez Gene 252864
UniGene
RefSeq NM_001159376 NM_145744
OMIM
CCDS CCDS50754 CCDS16902
HPRD
IMGT
MGI ID MGI:1934928
MGI Symbol Dusp15
EMBL AF357887 AL833801 BC116841 BC116843 BU924460
GenPept AAI16842 AAI16844 AAM00226 CAM23680
RNA Seq Atlas 252864

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca