InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Kif3b

Summary

InnateDB Gene

IDBG-210062.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kif3b

Gene Name

kinesin family member 3B

Synonyms

AI854312; AW549267; mKIAA0359

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027475

Encoded Proteins

IDBP-210066

kinesin family member 3B

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101350:
The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:153291413-153333390

Strand

Forward strand

Band

Transcripts

ENSMUST00000028977

ENSMUSP00000028977

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding
GO:0017048	Rho GTPase binding

Biological Process

GO:0007018	microtubule-based movement
GO:0008152	metabolic process
GO:0032467	positive regulation of cytokinesis
GO:0090307	spindle assembly involved in mitosis

Cellular Component

GO:0005813	centrosome
GO:0005819	spindle
GO:0005829	cytosol
GO:0005874	microtubule
GO:0005929	cilium
GO:0015630	microtubule cytoskeleton
GO:0016020	membrane
GO:0016939	kinesin II complex
GO:0030496	midbody
GO:0030990	intraciliary transport particle
GO:0070062	extracellular vesicular exosome