Version 5.4
Mus musculus Gene: Paox
Summary
InnateDB Gene IDBG-211671.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Paox
Gene Name polyamine oxidase (exo-N4-amino)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025464
Encoded Proteins
IDBP-211673
polyamine oxidase (exo-N4-amino)
IDBP-211675
polyamine oxidase (exo-N4-amino)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148832:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:140125657-140134334
Strand Forward strand
Band F4
Transcripts
ENSMUST00000026537 ENSMUSP00000026537
ENSMUST00000097967 ENSMUSP00000095580
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0016491 oxidoreductase activity
GO:0046592 polyamine oxidase activity
GO:0052899 N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
GO:0052901 spermine:oxygen oxidoreductase (spermidine-forming) activity
GO:0052902 spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity
GO:0052903 N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
GO:0052904 N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
Biological Process
GO:0006598 polyamine catabolic process
GO:0009446 putrescine biosynthetic process
GO:0009447 putrescine catabolic process
GO:0046203 spermidine catabolic process
GO:0046208 spermine catabolic process
GO:0055114 oxidation-reduction process
GO:1901307 positive regulation of spermidine biosynthetic process
Cellular Component
GO:0005782 peroxisomal matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000148832
View Gene Order
ENSBTAG00000018321
Not yet available
Pathways
NETPATH
REACTOME
REACT_249802
Phase 1 - Functionalization of compounds pathway
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_253147
Metabolism of polyamines pathway
REACT_243153
Interconversion of polyamines pathway
REACT_232343
Biological oxidations pathway
REACT_260206
PAOs oxidise polyamines to amines pathway
REACT_231002
Amine Oxidase reactions pathway
KEGG
mmu04146
Peroxisome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_14805
Interconversion of polyamines pathway
REACT_14820
Metabolism of polyamines pathway
REACT_505
PAOs oxidise polyamines to amines pathway
REACT_1875
Amine Oxidase reactions pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
REACT_13705
Phase 1 - Functionalization of compounds pathway
KEGG
hsa04146
Peroxisome pathway
INOH
PID NCI
integrin_a9b1_pathway
Alpha9 beta1 integrin signaling events
Cross-References
SwissProt Q8C0L6
TrEMBL Q3TXR6
UniProt Splice Variant
Entrez Gene 212503
UniGene Mm.410706
RefSeq NM_153783 XM_006536168 XM_006536169
OMIM
CCDS CCDS21965
HPRD
IMGT
MGI ID MGI:1916983
MGI Symbol Paox
EMBL AC109205 AF226656 AK030664 AK159137 BC033913 BC082783 CH466531
GenPept AAH33913 AAH82783 AAN40705 BAC27070 BAE34849 EDL17916
RNA Seq Atlas 212503

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca