Version 5.4
Mus musculus Gene: Ncoa5
Summary
InnateDB Gene IDBG-212528.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ncoa5
Gene Name nuclear receptor coactivator 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039804
Encoded Proteins
IDBP-212530
nuclear receptor coactivator 5
IDBP-401790
nuclear receptor coactivator 5
IDBP-401791
nuclear receptor coactivator 5
IDBP-535780
nuclear receptor coactivator 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124160:
This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this gene have been described. However, the full length nature of one of the variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:165000357-165034867
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000040381 ENSMUSP00000046388
ENSMUST00000121377 ENSMUSP00000113872
ENSMUST00000122070 ENSMUSP00000113166
ENSMUST00000123347
ENSMUST00000127545
ENSMUST00000153905 ENSMUSP00000116778
ENSMUST00000126685
ENSMUST00000141663
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0015629 actin cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124160
View Gene Order
ENSBTAG00000014186
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.233080 Mm.470785
RefSeq NM_144892 XM_006499368
OMIM
CCDS CCDS17068
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca