Version 5.4
Mus musculus Gene: Ano1
Summary
InnateDB Gene IDBG-212921.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ano1
Gene Name anoctamin 1, calcium activated chloride channel
Synonyms Tmem16a
Species Mus musculus
Ensembl Gene ENSMUSG00000031075
Encoded Proteins
IDBP-212923
anoctamin 1, calcium activated chloride channel
IDBP-400111
anoctamin 1, calcium activated chloride channel
IDBP-400110
anoctamin 1, calcium activated chloride channel
IDBP-540253
anoctamin 1, calcium activated chloride channel
IDBP-536002
anoctamin 1, calcium activated chloride channel
IDBP-534603
anoctamin 1, calcium activated chloride channel
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131620:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:144588549-144751974
Strand Reverse strand
Band F5
Transcripts
ENSMUST00000033393 ENSMUSP00000033393
ENSMUST00000118556 ENSMUSP00000113899
ENSMUST00000121758 ENSMUSP00000112616
ENSMUST00000131571
ENSMUST00000152531 ENSMUSP00000119653
ENSMUST00000155175 ENSMUSP00000120306
ENSMUST00000141632
ENSMUST00000131731 ENSMUSP00000118206
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005227 calcium activated cation channel activity
GO:0005229 intracellular calcium activated chloride channel activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006812 cation transport
GO:0006821 chloride transport
GO:0042391 regulation of membrane potential
GO:0060438 trachea development
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0034707 chloride channel complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000131620
View Gene Order
ENSBTAG00000009997
Not yet available
Pathways
NETPATH
REACTOME
REACT_196640
Stimuli-sensing channels pathway
REACT_268398
Orphan transporters pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_267716
Orphan transporters pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.26700 Mm.437507
RefSeq NM_001242349 NM_178642 XM_006508461 XM_006508462
OMIM
CCDS CCDS57600
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca