Version 5.4
Mus musculus Gene: Fmnl1
Summary
InnateDB Gene IDBG-212976.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fmnl1
Gene Name formin-like 1
Synonyms 8030453N10Rik; AI553564; Fmnl; Fnrl; Frls
Species Mus musculus
Ensembl Gene ENSMUSG00000055805
Encoded Proteins
IDBP-212978
formin-like 1
IDBP-267537
formin-like 1
IDBP-620218
formin-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184922:
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:103171107-103198901
Strand Forward strand
Band E1
Transcripts
ENSMUST00000042286 ENSMUSP00000046296
ENSMUST00000021322
ENSMUST00000107027 ENSMUSP00000102642
ENSMUST00000126425
ENSMUST00000154871
ENSMUST00000129726 ENSMUSP00000133299
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 55 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0005515 protein binding
GO:0005522 profilin binding
GO:0017048 Rho GTPase binding
GO:0032794 GTPase activating protein binding
GO:0048365 Rac GTPase binding
GO:0051015 actin filament binding
Biological Process
GO:0006929 substrate-dependent cell migration
GO:0007010 cytoskeleton organization
GO:0008360 regulation of cell shape
GO:0009987 cellular process
GO:0016043 cellular component organization
GO:0030036 actin cytoskeleton organization
GO:0030866 cortical actin cytoskeleton organization
GO:0051014 actin filament severing
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0045335 phagocytic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184922
View Gene Order
ENSBTAG00000004196
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.138913
RefSeq NM_001077698 NM_019679 XM_006533842 XM_006533843
OMIM
CCDS CCDS36348 CCDS36349
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca