Version 5.4
Mus musculus Gene: Gmeb2
Summary
InnateDB Gene IDBG-214048.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gmeb2
Gene Name glucocorticoid modulatory element binding protein 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038705
Encoded Proteins
IDBP-214050
glucocorticoid modulatory element binding protein 2
IDBP-531760
glucocorticoid modulatory element binding protein 2
IDBP-531877
glucocorticoid modulatory element binding protein 2
IDBP-533763
glucocorticoid modulatory element binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101216:
This gene is a member of KDWK gene family. The product of this gene associates with GMEB1 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation by the glucocorticoid receptor bound to glucocorticoid response elements. This gene appears to use multiple polyadenylation sites. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:181251449-181288035
Strand Reverse strand
Band H4
Transcripts
ENSMUST00000049032 ENSMUSP00000037075
ENSMUST00000141110 ENSMUSP00000115853
ENSMUST00000123148
ENSMUST00000130475 ENSMUSP00000116479
ENSMUST00000141003 ENSMUSP00000116854
ENSMUST00000147665
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0004871 signal transducer activity
GO:0046872 metal ion binding
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
GO:2001141 regulation of RNA biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101216
View Gene Order
ENSBTAG00000014769
Not yet available
Cross-References
SwissProt P58929
TrEMBL A2AS07
UniProt Splice Variant
Entrez Gene 229004
UniGene Mm.470334
RefSeq NM_198169 XM_006500602 XM_006500603 XM_006500604 XM_006500605 XM_006500606
OMIM
CCDS CCDS17206
HPRD
IMGT
MGI ID MGI:2652836
MGI Symbol Gmeb2
EMBL AL845506 BC029763 BC059066
GenPept AAH29763 AAH59066
RNA Seq Atlas 229004

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca