Version 5.4
Mus musculus Gene: Nup85
Summary
InnateDB Gene IDBG-214324.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nup85
Gene Name nucleoporin 85
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020739
Encoded Proteins
IDBP-214326
nucleoporin 85
IDBP-542896
nucleoporin 85
IDBP-542897
nucleoporin 85
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125450:
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP85 is part of one such subcomplex, Nup107-160. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:115564434-115583985
Strand Forward strand
Band E2
Transcripts
ENSMUST00000021085 ENSMUSP00000021085
ENSMUST00000135893
ENSMUST00000144473 ENSMUSP00000116069
ENSMUST00000140986 ENSMUSP00000117333
ENSMUST00000143351
ENSMUST00000127126
ENSMUST00000138998
ENSMUST00000128745
ENSMUST00000134209
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0031727 CCR2 chemokine receptor binding
Biological Process
GO:0006935 chemotaxis
GO:0015031 protein transport
GO:0019221 cytokine-mediated signaling pathway
GO:0030032 lamellipodium assembly
GO:0048246 macrophage chemotaxis
GO:0051028 mRNA transport
Cellular Component
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031080 nuclear pore outer ring
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125450
View Gene Order
ENSBTAG00000016126
Not yet available
Pathways
NETPATH
REACTOME
REACT_196648
Nuclear Envelope Breakdown pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_189085
Disease pathway
REACT_196650
Nuclear Pore Complex (NPC) Disassembly pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_204192
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
REACT_188804
Cell Cycle pathway
REACT_188937
Metabolism pathway
REACT_241408
M Phase pathway
REACT_270446
Transcriptional regulation by small RNAs pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_253543
Glucose transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_240125
Hexose transport pathway
REACT_203949
Glycogen storage diseases pathway
REACT_233572
Gene Expression pathway
REACT_206535
Regulatory RNA pathways pathway
REACT_250557
Mitotic Prophase pathway
REACT_203841
Myoclonic epilepsy of Lafora pathway
REACT_202512
Mitotic Anaphase pathway
REACT_248571
Metabolism of carbohydrates pathway
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115831
ISG15 antiviral mechanism pathway
REACT_6804
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
REACT_212
Glucose transport pathway
REACT_9441
Hexose transport pathway
REACT_9395
Nuclear import of Rev protein pathway
REACT_7991
Vpr-mediated nuclear import of PICs pathway
REACT_6190
Rev-mediated nuclear export of HIV RNA pathway
REACT_6354
Viral Messenger RNA Synthesis pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_6167
Influenza Infection pathway
REACT_6757
Interactions of Vpr with host cellular proteins pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_115676
Antiviral mechanism by IFN-stimulated genes pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_267668
Transcriptional regulation by small RNAs pathway
REACT_163931
Nuclear Pore Complex (NPC) Disassembly pathway
REACT_6152
Influenza Viral RNA Transcription and Replication pathway
REACT_25229
Interferon Signaling pathway
REACT_115566
Cell Cycle pathway
REACT_6900
Immune System pathway
REACT_910
M Phase pathway
REACT_6256
HIV Life Cycle pathway
REACT_1275
Mitotic Anaphase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_6185
HIV Infection pathway
REACT_6145
Influenza Life Cycle pathway
REACT_111217
Metabolism pathway
REACT_6288
Host Interactions of HIV factors pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_6916
Interactions of Rev with host cellular proteins pathway
REACT_71
Gene Expression pathway
REACT_160255
Nuclear Envelope Breakdown pathway
REACT_116125
Disease pathway
REACT_200833
Glycogen storage diseases pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
REACT_12472
Regulatory RNA pathways pathway
REACT_221274
Metabolism of carbohydrates pathway
REACT_222460
SLC-mediated transmembrane transport pathway
REACT_203892
Hexose transport pathway
REACT_216366
M Phase pathway
REACT_212887
Separation of Sister Chromatids pathway
REACT_201906
Nuclear Pore Complex (NPC) Disassembly pathway
REACT_215084
Mitotic Metaphase and Anaphase pathway
REACT_219973
Myoclonic epilepsy of Lafora pathway
REACT_211185
Mitotic Anaphase pathway
REACT_209409
Nuclear Envelope Breakdown pathway
REACT_226022
Gene Expression pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_269816
Transcriptional regulation by small RNAs pathway
REACT_214934
Cell Cycle pathway
REACT_210324
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
REACT_204270
Glucose transport pathway
REACT_211129
Glycogen storage diseases pathway
REACT_219139
Metabolism pathway
REACT_211448
Mitotic Prophase pathway
REACT_209545
Resolution of Sister Chromatid Cohesion pathway
REACT_210892
Regulatory RNA pathways pathway
REACT_203101
Mitotic Prometaphase pathway
REACT_207087
Disease pathway
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001002929 XM_006533671
OMIM
CCDS CCDS25640
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca