Version 5.4
Mus musculus Gene: Pcdhb20
Summary
InnateDB Gene IDBG-217540.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcdhb20
Gene Name protocadherin beta 20
Synonyms Pcdhb14; PcdhbT
Species Mus musculus
Ensembl Gene ENSMUSG00000046191
Encoded Proteins
IDBP-702543
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120327:
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:37504264-37507658
Strand Forward strand
Band B3
Transcripts
ENSMUST00000052179 ENSMUSP00000137038
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000120327
View Gene Order
ENSBTAG00000007349
Not yet available
Cross-References
SwissProt
TrEMBL Q91XZ9
UniProt Splice Variant
Entrez Gene 93891
UniGene Mm.172449 Mm.470761
RefSeq NM_053145
OMIM
CCDS CCDS57120
HPRD
IMGT
MGI ID MGI:2136758
MGI Symbol Pcdhb20
EMBL AC020967 AK045399 AK046137 AY013782 BC031895
GenPept AAH31895 AAK26071 BAC32346 BAC32611
RNA Seq Atlas 93891

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca