Version 5.4
Homo sapiens Gene: TMSB4Y
Summary
InnateDB Gene IDBG-220.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMSB4Y
Gene Name thymosin beta 4, Y-linked
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154620
Encoded Proteins
IDBP-224
thymosin beta 4, Y-linked
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene lies within the male specific region of chromosome Y. Its homolog on chromosome X escapes X inactivation and encodes an actin sequestering protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome Y:13703567-13706024
Strand Forward strand
Band q11.221
Transcripts
ENST00000284856 ENSP00000284856
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0008064 regulation of actin polymerization or depolymerization
GO:0030036 actin cytoskeleton organization
GO:0042989 sequestering of actin monomers
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
INOH
PID NCI
Cross-References
SwissProt O14604
TrEMBL
UniProt Splice Variant
Entrez Gene 9087
UniGene Hs.159201
RefSeq NM_004202
HUGO HGNC:11882
OMIM 400017
CCDS CCDS14786
HPRD 02458
IMGT
EMBL AC006371 AF000989 BC022482 BC119763 BC119764
GenPept AAC51836 AAD54509 AAI19764 AAI19765
RNA Seq Atlas 9087

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca