Version 5.4
Mus musculus Gene: Lax1
Summary
InnateDB Gene IDBG-221584.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lax1
Gene Name lymphocyte transmembrane adaptor 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000051998
Encoded Proteins
IDBP-627280
lymphocyte transmembrane adaptor 1
IDBP-788199
lymphocyte transmembrane adaptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122188:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:133679091-133690108
Strand Reverse strand
Band E4
Transcripts
ENSMUST00000169295 ENSMUSP00000131126
ENSMUST00000189524 ENSMUSP00000140039
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0042169 SH2 domain binding
Biological Process
GO:0000188 inactivation of MAPK activity
GO:0006955 immune response
GO:0035556 intracellular signal transduction
GO:0042113 B cell activation
GO:0046649 lymphocyte activation
GO:0048305 immunoglobulin secretion
GO:0050851 antigen receptor-mediated signaling pathway
GO:0050868 negative regulation of T cell activation
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000122188
View Gene Order
ENSBTAG00000012349
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.36534
RefSeq NM_001159649 NM_172842 XM_006529557
OMIM
CCDS CCDS35711
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca