Homo sapiens Gene: MED31
Summary
InnateDB Gene IDBG-22470.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED31
Gene Name mediator complex subunit 31
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000108590
Encoded Proteins
mediator complex subunit 31
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:6643315-6651634
Strand Reverse strand
Band p13.1
Transcripts
ENST00000225728 ENSP00000225728
ENST00000575519
ENST00000575197 ENSP00000458248
ENST00000574128 ENSP00000459723
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 88 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 88 [view]
Protein-Protein 87 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0005515 protein binding
GO:0032403 protein complex binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006461 protein complex assembly
GO:0010467 gene expression
GO:0048147 negative regulation of fibroblast proliferation
GO:0060173 limb development
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0016592 mediator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
PPARA activates gene expression pathway
Generic Transcription Pathway pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Transcriptional regulation of white adipocyte differentiation pathway
Metabolism pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Gene Expression pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9Y3C7
TrEMBL I3L0P8 I3L2J1
UniProt Splice Variant
Entrez Gene 51003
UniGene Hs.567493
RefSeq NM_016060 XM_005256671
HUGO HGNC:24260
OMIM
CCDS CCDS11078
HPRD
IMGT
EMBL AC004706 AF151883 AK311875 BC012539 CH471108
GenPept AAD34120 AAH12539 BAG34816 EAW90301
RNA Seq Atlas 51003