Version 5.4
Homo sapiens Gene: FBXO16
Summary
InnateDB Gene IDBG-235508.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXO16
Gene Name F-box protein 16
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000214050
Encoded Proteins
IDBP-14917
F-box protein 16
IDBP-14919
F-box protein 16
IDBP-478626
F-box protein 16
IDBP-485352
F-box protein 16
IDBP-479124
F-box protein 16
IDBP-475678
F-box protein 16
IDBP-482227
F-box protein 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:28348287-28490318
Strand Reverse strand
Band p21.1
Transcripts
ENST00000380254 ENSP00000369604
ENST00000346498 ENSP00000341416
ENST00000521548 ENSP00000428902
ENST00000518248 ENSP00000431064
ENST00000522609
ENST00000518734 ENSP00000429687
ENST00000520481
ENST00000517436
ENST00000517673 ENSP00000429390
ENST00000518016
ENST00000519471 ENSP00000428683
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034532
View Gene Order
ENSBTAG00000034626
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.659190 Hs.741522
RefSeq NM_001258211 NM_172366
HUGO
OMIM
CCDS CCDS59099 CCDS6068
HPRD 16347
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca