Homo sapiens Gene: EIF3G
Summary
InnateDB Gene IDBG-26498.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF3G
Gene Name eukaryotic translation initiation factor 3, subunit G
Synonyms eIF3-delta; EIF3-P42; eIF3-p44; EIF3S4;
Species Homo sapiens
Ensembl Gene ENSG00000130811
Encoded Proteins
eukaryotic translation initiation factor 3, subunit G
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:10115017-10119920
Strand Reverse strand
Band p13.2
Transcripts
ENST00000253108 ENSP00000253108
ENST00000593066 ENSP00000466943
ENST00000587168
ENST00000589454 ENSP00000466860
ENST00000593054 ENSP00000467187
ENST00000588709 ENSP00000465882
ENST00000587993 ENSP00000468313
ENST00000589458
ENST00000589674
ENST00000590158
ENST00000593095 ENSP00000465933
ENST00000587681
ENST00000590647
ENST00000587146 ENSP00000468159
ENST00000592485
ENST00000586151 ENSP00000465925
ENST00000589009
ENST00000590940
ENST00000587590
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 80 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 80 [view]
Protein-Protein 80 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0006412 translation
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:0010467 gene expression
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Eukaryotic Translation Initiation pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Formation of a pool of free 40S subunits pathway
Translation pathway
Translation initiation complex formation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Ribosomal scanning and start codon recognition pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Gene Expression pathway
KEGG
RNA transport pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.529059
RefSeq NM_003755
HUGO
OMIM
CCDS CCDS12227
HPRD 04886
IMGT
EMBL
GenPept
RNA Seq Atlas