Homo sapiens Gene: FABP4
Summary
InnateDB Gene IDBG-26715.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FABP4
Gene Name fatty acid binding protein 4, adipocyte
Synonyms A-FABP; AFABP; ALBP; aP2; HEL-S-104;
Species Homo sapiens
Ensembl Gene ENSG00000170323
Encoded Proteins
fatty acid binding protein 4, adipocyte
fatty acid binding protein 4, adipocyte
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:81478419-81483263
Strand Reverse strand
Band q21.13
Transcripts
ENST00000256104 ENSP00000256104
ENST00000518669
ENST00000522659 ENSP00000428385
ENST00000521734
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005504 fatty acid binding
Biological Process
GO:0001816 cytokine production
GO:0006469 negative regulation of protein kinase activity
GO:0006810 transport
GO:0019433 triglyceride catabolic process
GO:0042632 cholesterol homeostasis
GO:0044281 small molecule metabolic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050729 positive regulation of inflammatory response
GO:0050872 white fat cell differentiation
GO:0050873 brown fat cell differentiation
GO:0071285 cellular response to lithium ion
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005811 lipid particle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Transcriptional regulation of white adipocyte differentiation pathway
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis pathway
Metabolism pathway
Lipid digestion, mobilization, and transport pathway
KEGG
PPAR signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
AP-1 transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001442
HUGO
OMIM
CCDS CCDS6230
HPRD 02698
IMGT
EMBL
GenPept
RNA Seq Atlas