Version 5.4
| Mus musculus Gene: Cyp4a12b | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-268553.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Cyp4a12b | ||||||||||
| Gene Name | cytochrome P450, family 4, subfamily a, polypeptide 12B | ||||||||||
| Synonyms | BC060945; Cyp4a12 | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000078597 | ||||||||||
| Encoded Proteins |
cytochrome P450, family 4, subfamily a, polypeptide 12B
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187048:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 4:115411624-115439034 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | D1 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
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Gene ID
Gene Order
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME | |||||||||||
| KEGG |
Retinol metabolism pathway
Arachidonic acid metabolism pathway
PPAR signaling pathway pathway
Fatty acid degradation pathway
Vascular smooth muscle contraction pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Synthesis of Leukotrienes (LT) and Eoxins (EX) pathway
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) pathway
Arachidonic acid metabolism pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Fatty acids pathway
Miscellaneous substrates pathway
Eicosanoids pathway
Metabolism of lipids and lipoproteins pathway
Cytochrome P450 - arranged by substrate type pathway
Metabolism pathway
Biological oxidations pathway
Phase 1 - Functionalization of compounds pathway
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| KEGG |
Arachidonic acid metabolism pathway
Retinol metabolism pathway
Fatty acid degradation pathway
Vascular smooth muscle contraction pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | A2A974 O35650 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 13118 | ||||||||||
| UniGene | Mm.448292 | ||||||||||
| RefSeq | NM_172306 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS18490 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:3611747 | ||||||||||
| MGI Symbol | Cyp4a12b | ||||||||||
| EMBL | AL627182 Y10221 Y10222 | ||||||||||
| GenPept | CAA71269 | ||||||||||
| RNA Seq Atlas | 13118 | ||||||||||