Version 5.4
| Homo sapiens Gene: TRIM6 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-27325.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | TRIM6 | ||||||||||||||||||
| Gene Name | tripartite motif containing 6 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000121236 | ||||||||||||||||||
| Encoded Proteins |
tripartite motif containing 6
tripartite motif containing 6
tripartite motif containing 6
tripartite motif containing 6
tripartite motif containing 6
tripartite motif containing 6
tripartite motif containing 6
tripartite motif containing 6
tripartite motif containing 6
tripartite motif containing 6
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| InnateDB Annotation | |||||||||||||||||||
| Summary |
TRIM6 was identified in a systematic screen for positive regulators of innate immune responses.
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| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 11:5596109-5612958 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | p15.4 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
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Gene ID
Gene Order
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| Cross-References | |||||||||||||||||||
| SwissProt | Q9C030 | ||||||||||||||||||
| TrEMBL | C9JNQ0 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 117854 | ||||||||||||||||||
| UniGene | |||||||||||||||||||
| RefSeq | NM_001198645 NM_001003818 NM_001198644 NM_058166 | ||||||||||||||||||
| HUGO | HGNC:16277 | ||||||||||||||||||
| OMIM | 607564 | ||||||||||||||||||
| CCDS | CCDS55738 CCDS31389 CCDS31390 | ||||||||||||||||||
| HPRD | 12123 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AB039903 AC015691 AF220030 AK027664 AK290172 AK293295 AK298301 AK316178 AK316289 BC047564 CH471064 | ||||||||||||||||||
| GenPept | AAG53484 AAH47564 BAB17050 BAB55276 BAF82861 BAG56816 BAG60556 BAH14549 BAH14660 EAW68783 EAW68785 | ||||||||||||||||||
| RNA Seq Atlas | 117854 | ||||||||||||||||||