Homo sapiens Gene: TRIM16
Summary
InnateDB Gene IDBG-281555.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM16
Gene Name tripartite motif containing 16
Synonyms EBBP;
Species Homo sapiens
Ensembl Gene ENSG00000221926
Encoded Proteins
tripartite motif containing 16
tripartite motif containing 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:15627960-15684311
Strand Reverse strand
Band p12
Transcripts
ENST00000336708 ENSP00000338989
ENST00000416464 ENSP00000399918
ENST00000473368
ENST00000473540
ENST00000460728
ENST00000473659
ENST00000494759 ENSP00000465169
ENST00000577326
ENST00000581224
ENST00000577886 ENSP00000462903
ENST00000582708
ENST00000579219 ENSP00000463639
ENST00000579630
ENST00000578237 ENSP00000463188
ENST00000580388
ENST00000578744 ENSP00000465907
ENST00000582182
ENST00000579843
ENST00000577446 ENSP00000467031
ENST00000577372 ENSP00000463293
ENST00000580110 ENSP00000464072
ENST00000581200 ENSP00000463360
ENST00000584142
ENST00000579535
ENST00000579272
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0019966 interleukin-1 binding
GO:0032089 NACHT domain binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0032526 response to retinoic acid
GO:0043966 histone H3 acetylation
GO:0043967 histone H4 acetylation
GO:0045618 positive regulation of keratinocyte differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046683 response to organophosphorus
GO:0048386 positive regulation of retinoic acid receptor signaling pathway
GO:0050718 positive regulation of interleukin-1 beta secretion
GO:0060416 response to growth hormone
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0016605 PML body
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.638613 Hs.735748
RefSeq NM_006470
HUGO
OMIM
CCDS CCDS11171
HPRD 15552
IMGT
EMBL
GenPept
RNA Seq Atlas