Version 5.4
Homo sapiens Gene: KLHL8
Summary
InnateDB Gene IDBG-28868.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLHL8
Gene Name kelch-like 8 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145332
Encoded Proteins
IDBP-28870
kelch-like 8 (Drosophila)
IDBP-373878
kelch-like 8 (Drosophila)
IDBP-478233
kelch-like 8 (Drosophila)
IDBP-474568
kelch-like 8 (Drosophila)
IDBP-478097
kelch-like 8 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:87160103-87240314
Strand Reverse strand
Band q22.1
Transcripts
ENST00000273963 ENSP00000273963
ENST00000425278 ENSP00000408854
ENST00000498875 ENSP00000426451
ENST00000506985 ENSP00000426361
ENST00000512111 ENSP00000424131
ENST00000505388
ENST00000504029
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0031463 Cul3-RING ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029312
View Gene Order
ENSBTAG00000002455
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.106601 Hs.715202
RefSeq NM_001292003 NM_001292006 NM_001292007 NM_020803 XM_005263153
HUGO
OMIM
CCDS CCDS3617 CCDS75163
HPRD 13928
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca